Sabiia Seb
PortuguêsEspañolEnglish
Embrapa
        Busca avançada

Botão Atualizar


Botão Atualizar

Registro completo
Provedor de dados:  ArchiMer
País:  France
Título:  Exposures of zebrafish through diet to three environmentally relevant mixtures of PAHs produce behavioral disruptions in unexposed F1 and F2 descendant
Autores:  Vignet, Caroline
Joassard, Lucette
Lyphout, Laura
Guionnet, Tiphaine
Goubeau, Manon
Le Menach, Karyn
Brion, Francois
Kah, Olivier
Chung, Bon-chu
Budzinski, Helene
Begout, Marie-laure
Cousin, Xavier
Data:  2015-11
Ano:  2015
Palavras-chave:  Danio rerio
Polycyclic aromatic hydrocarbon
Offspring
Transgenerational effect
Heavy oil
Light crude oil
Locomotor activity
Photomotor response
Anxiety-like behavior
Resumo:  The release of polycyclic aromatic hydrocarbons (PAHs) into the environment has increased very substantially over the last decades. PAHs are hydrophobic molecules which can accumulate in high concentrations in sediments acting then as major secondary sources. Fish contamination can occur through contact or residence nearby sediments or though dietary exposure. In this study, we analyzed certain physiological traits in unexposed fish (F1) issued from parents (F0) exposed through diet to three PAH mixtures at similar and environmentally relevant concentrations but differing in their compositions. For each mixture, no morphological differences were observed between concentrations. An increase in locomotor activity was observed in larvae issued from fish exposed to the highest concentration of a pyrolytic (PY) mixture. On the contrary, a decrease in locomotor activity was observed in larvae issued from heavy oil mixture (HO). In the case of the third mixture, light oil (LO), a reduction of the diurnal activity was observed during the setup of larval activity. Behavioral disruptions persisted in F1-PY juveniles and in their offspring (F2). Endocrine disruption was analyzed using cyp19a1b:GFP transgenic line and revealed disruptions in PY and LO offspring. Since no PAH metabolites were dosed in larvae, these findings suggest possible underlying mechanisms such as altered parental signaling molecule and/or hormone transferred in the gametes, eventually leading to early imprinting. Taken together, these results indicate that physiological disruptions are observed in offspring of fish exposed to PAH mixtures through diet.
Tipo:  Text
Idioma:  Inglês
Identificador:  https://archimer.ifremer.fr/doc/00259/37030/35688.pdf

DOI:10.1007/s11356-015-4157-8

https://archimer.ifremer.fr/doc/00259/37030/
Editor:  Springer Heidelberg
Formato:  application/pdf
Fonte:  Environmental Science And Pollution Research (0944-1344) (Springer Heidelberg), 2015-11 , Vol. 22 , N. 21 , P. 16371-16383
Direitos:  Springer-Verlag Berlin Heidelberg 2015

info:eu-repo/semantics/openAccess

restricted use
Fechar
 

Empresa Brasileira de Pesquisa Agropecuária - Embrapa
Todos os direitos reservados, conforme Lei n° 9.610
Política de Privacidade
Área restrita

Embrapa
Parque Estação Biológica - PqEB s/n°
Brasília, DF - Brasil - CEP 70770-901
Fone: (61) 3448-4433 - Fax: (61) 3448-4890 / 3448-4891 SAC: https://www.embrapa.br/fale-conosco

Valid HTML 4.01 Transitional